Dr. Persichetti traveled to Portland after graduation from the Baltimore College of Dental Surgery at the University of Maryland. The purpose of his visit to Portland was to receive advanced training in general dentistry in a residency program at the Oregon Health Sciences University. After completing his year of residency, Dr. Persichetti joined the faculty at the Oregon Health Sciences University School of Dentistry. He was an associate professor at the dental school for thirteen years. He joined Downtown Dental Associates on a full time basis in 1997. Dr. Persichetti continues to teach at the dental school one day a week.

Dr. Persichetti's practice philosophy is based upon a desire to blend art, science and intuition to meet the treatment needs and personal concerns of his patients. His approach to dental practice is based upon an uncompromising concern and personal commitment to the welfare of his patients, dedication to quality, and innovation. Through his commitment to lifelong learning, Dr. Persichetti has come to understand when to embrace the latest dental technologies and when to choose the tried and true methods. His practice emphasizes all aspects of adult and children's dentistry.

Dr. Persichetti is a Fellow in the Academy of General Dentistry, the American College of Dentists and the International College of Dentists. He is past president of the Oregon Academy of General Dentistry and currently serves on the Academy of General Dentistry's Council on Dental Education.